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mRNA technology
Messenger RNA, or mRNA, was discovered in the early 1960s. mRN is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. The administration of a nucleoside-modified messenger RNA sequence can cause a cell to make a specfic protein, which can treat a disease or function as a vaccine
5 Facts you should know
FACT
mRNA, or messenger ribonucleic acid, is a single-stranded RNA molecule that carries the genetic information that is derived from DNA
FACT
RNA is a single strand of code letters (nucleotides), while DNA is double-stranded. The RNA code contains uracil (U) instead of thymine (T)
FACT
The structural features of the mRNA – the U in the code, its single-stranded shape, ribose sugar and its specific sequence – are responsible for its short half-life
FACT
mRNA provides the “code” for almost about any protein – which makes it valuable for the treatment (or prevention) of diseases
FACT
The primary challenges of RNA therapy center on delivering the RNA to the appropriate cells
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