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5 Facts you should know about
Infections in the
WHIM syndrome
1
WHIM patients with warts characteristically have numerous warts on hands, feet, and trunk
2
WHIM patients have greater problem with bacterial infections - particularly with encapsulated organisms - than with virus infections
3
Common pathogens include, but are not limited to, Haemophilus influenzae, Streptococcus pneumoniae, Klebsiella pneumoniae, Staphylococcus aureus, and Proteus mirabilis
4
WHIM patients are particularly susceptible to infection with HPV, which in these patients not only causes warts, but also results in condyloma acuminata and dysplastic lesions of the genital-anal mucosa
5
Recurrent pneumonias may lead to severe bronchiectasis - patients who develop bronchiectasis may also suffer from chronic infections with Pseudomonas aerugenosa or Burkhoderia cepacia
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